Flames of the Blood Hand 

Instant
Flames of the Blood Hand deals 4 damage to target player or planeswalker. The damage can't be prevented. If that player or that planeswalker's controller would gain life this turn, that player gains no life instead.
Legality
standardNOT LEGALpioneerNOT LEGALmodernLEGALlegacyLEGALvintageLEGALcommanderLEGAL